Gel 502

Designed for painful leg ulcers

Available as a private label or Gentell-branded for distributors.

Kick-start the wound healing process

14 days between images. 10 patient study, WHRU Cardiff. Significant increase in granulation tissue over 14 day period (p<0.02).

Features

Subjective analysis to aid product comparison.

  • Encourages debridement of necrotic tissue

  • Increases granulation tissue of chronic wounds

  • Soothes and cool to minimize discomfort

  • Protects against wound dehydration

  • Barrier to the growth of bacteria

  • Helps prevent maceration of the peri-wound area

  • Can be cut to fit most wounds (non-adhesive only)

Gel 502 is a 50% water-content ionic polymer sheet hydrogel dressing.

It’s available in a range of sizes, with and without an adhesive border.

Construction

Tackles wound pain

WHRU Study1. Pain associated with the wound was significantly reduced (p<0.05) corresponding to a greater than 50% reduction in the median visual scale pain score. WHRU 2007

14 day, single-centre, prospective, non-randomised, non-blinded pilot observational clinical trial involving 10 individuals who had venous or mixed aetiology leg ulcers that had persisted for at least 3 months where the wound area had not changed by more than 25% during the previous month. Various studies have shown hydrogel dressings have the ability to inhibit proteolysis, resulting in the reduction in MMPs (in vitro) and wound pain.1 A subsequent evaluation2 was conducted using 11 participants (8 females, 3 males) at The Wound Healing Research Unit, Cardiff University, UK. Despite undergoing up to 2 years of wound management with other dressings, all patients showed a significant improvement in terms of reduction of slough and increase in granulation tissue within just 14 days of using Gel 502 Dressings.

MMP Modulation

MMPs (Matrix Metallo Proteinases) are enzymes which clear away debris in the wound, including dead tissue. But when MMP levels are too high, they damage healthy cells and tissue. Chronic wounds have significantly higher levels of MMPs than acute wounds, which in part explains why they take much longer to heal.

In several separate studies, the Pro-ionic™ copolymer system in this product has been demonstrated in-vitro to be a powerful protease modulator (MMP-9, MMP-2, Human Neutrophil Elastase). This suggests that it may have a beneficial action by reducing the detrimental effects of proteolytic enzymes in vivo, and may explain the consistently positive clinical results with dressings based on Pro-ionic™ co-polymers.

Improved Absorption

Unlike typical sheet hydrogels (non-ionic systems), Gel 502 is based on an ionic polymer system. Among other properties, it’s therefore super-absorbent.

The result? A reduced risk of maceration if exudate levels increase in use.

Up to 91% inhibition of HuNE activity in 24h

Human Neutrophil Elastase. (p<0.001) data on file.

Management of wound bacteria

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Our hydrogel polymers are able to absorb micro-organisms from the surface where they remain viable for varying periods of time.

The ease of recovery of the absorbed bacteria is dependent on the method used. Very extensive crushing (disruption of the gel structure) of the gel is required to recover the bacteria.

In the clinical setting, this capability - to absorb the bacteria within the gel polymer structure - may enable Pro-ionic™  hydrogels to significantly reduce bacteria levels at the skin or wound surface.

Available in your own brand or Gentell brand.